[Comment] Global emergence of SARS-CoV-2 variants: new foresight needed for improved vaccine efficacy

Apart from COVID-19-appropriate behaviour, effective vaccine coverage is the single most important intervention needed to control the ongoing SARS-CoV-2 pandemic. Although several vaccines are being used under emergency use authorisation, worldwide vaccination coverage will only be achieved when vaccine availability exceeds vaccine demand. Globally, several prominent institutions, universities, and leading pharmaceutical companies have successfully developed COVID-19 vaccine candidates that have progressed to clinical trials.